Yea, I would never try to kill a raid boss with randoms.
Luckily I have 2 other friends with Borderlands 2 that I know IRL. We were able to kill Terramorphous without a forth (and without the Bee/Conference Call)
I played with randoms once, they just pretty much stole all the good loot, killed everything that I needed to kill while I was downed, and kept trying to duel me. One guy kept trying to duel me so I accepted and whipped his ass, after that I left and vowed to not play with randoms. :laugh: