Small things like Raiden affirming to Fujin that the Elder Gods can't destroy the Amulet, but in the comic, he is asking them to destroy it.
No harm in asking them if they could, anyway. That line was just there for the readers to know that it couldn't be destroyed, though.
Or when Cassie arrives on Outworld like she has never been there, and no mentions of being there. She even acts like she doesn't know Erron Black.
It's left vague enough that they could easily have met before. Their past meetings weren't exactly important in that situation, Erron wanted to know what they were doing in Outworld at that moment.
Hanzo mentions that he was a volunteer in the comics, whic makes sense. Yet, when Raiden happens to free some revenants from "Baldie"'s control, Scorpion does lose something, not his skin color, but his eyes go back to normal, as if he had some control over him (when even on MK9 it was obvious that he was free and was making the wrong choices).
That was to signify he was brought back to life, like the others, not freed from any mind control. He's not a spectre anymore himself, although he still has the powers.
While in the comics Suchin is killed by Red Dragon goons, on Takeda/Kenshi's ending it's revealed that she was killed by Daegon himself.
Kenshi also said in the story mode that she was killed by Red Dragon assassins, not Daegon himself. I think I'll take that line and the comic as more reliable sources than the arcade ending.
The Amulet was said to be protected not by Kamidogu, as in the comics, but by Raiden himself, with personal security (S.F, shaolin).
The comic takes place 10 years before and a lot could happen, it's obvious the Kamidogu are going to be gathered together at some point and the amulet is going to be released from the dimension it's locked in. So Raiden's going to have to resort to locking it away in a military base instead as per the game's plot.
Takeda asks why they can't go straight to the SKy Temple in the game, and Kung Jin explains why, but in the comics, Takeda and Hanzo go there BY FOOT (this one is as disturbing as Cassie not knowing Erron Black).
Wait, what's the problem here? Takeda and Scorpion didn't fly a plane there, so he wouldn't know they couldn't just land there. Given that Kung Jin got in there when he was just a thief, I'm sure Takeda and Scorpion would have been able to as well. As Chapter 1 showed, you just have to find and go through the underground portal.
On D'vorah's chapter, at the 25's, they go back FIVE YEARS, to show the coup d'etat. The problem is, in the comics, by the 15 years mark, Kotal mentions he has been battling Mileena for TEN YEARS.
That had to have been an error. They talk like the Netherrealm War is still going on, but that's impossible. Someone just messed up there and put "five years ago" instead of "twenty years ago."
Don't know about you, but I stick with the game. Seems like that story of "we are working together" between Kittelsen and NRS story team wasn't that right...
A lot of these are really minor or not really errors at all. You're going to get that with any mass-media project with more than one writer. The only one that's really a problem is Cassie talking about Outworld's skies--maybe she just remembered them as purple? Heck, you could even take her "no substitute for experience" line as her about to talk about her past ventures in Outworld, if you wanted to.