1. Scorpion
2. Sub-Zero
3. Cassie Cage
4. Jacqui Briggs
5. Kung Jin
6. Takeda
7. Kotal Kahn
8. D'Vorah
9. Erron Black
10. Ferra/Torr
11. Reptile
12. Raiden
13. Liu Kang
14. Kitana
15. Reiko
16. Tremor
17. Jade
18. Fujin
19. Kai
20. Nitara
21. Skarlet
22. Moloch
23. Drahmin
24. Rain
25. Li Mei
26. Cyrax
27. Ermac
28. Onaga
DLC Pack #1 (The Black Dragon Live On)
1. Kano's son
2. Jarek
3. Revenant Kabal
4. Kira (redesigned with a new hair color, preferably navy blue or a deep purple)
DLC Pack #2
1. Spawn
2. Havik
3. Noob Saibot
4. New female Saurian named Viper
A few new additions to story
-Fujin is the new protector of Earthrealm and is grooming Kai, who is shown to be much younger in this timeline, to be the next champion. He and Cassie have a bumpy relationship at first but things appear to be moving toward a mutual romantic interest later on.
-Cyrax has been reprogrammed by Jax, Johnny, and Sonya, who make cameo appearances, to serve in the Special Forces. He notes that the Lin Kuei has Sektor's robotic body, but Smoke was stolen from the Special Forces lab by a black ninja that seemed oddly familiar for some reason.
-The Serpentine Sect: These are Onaga's most trusted allies who have worked to ensure that his return is successful. It is a trio that consists of Reptile, Viper, and Li Mei. They carry out his most important tasks upon his return, including the murder of Kung Jin as a blood sacrifice.
-Kano has been arrested and his son is the leader of the new Black Dragon, who has been supplying the Netherrealm with bombs from the Dream Realm. The team consists of himself, Tremor, Jarek, and Kira, who later reveals that she is Kano's daughter and begins a personal rivalry with Cassie Cage. The new Black Dragon has also come to be in possession of Kabal's body and are debating on what to do with it.
-The Serpentine Sect feigns an alliance with Liu Kang, whom they call the "true Dragon King" and lead him and Kitana into a trap. Raiden faces Liu Kang and kills him in 1 on 1 combat. The mysterious woman in Jade's ending whisks Kitana away in a thick, murky green fog.
-Moloch and Drahmin fight together as one sub boss.
-The final fight is between Raiden and Onaga, until Rain shows up with an ancient Edenian weapon sealed away by Argus and it becomes a three way fight. Rain manages to mortally wound Raiden.
-Onaga, with the aid of a distraction from the Serpentine Sect, kills Rain, which awakens Taven and Daegon and leads into the next game.