L.A. Noire seems interesting, so does Uncharted 3, but MK9 will own every single game this year!
Except, of course, if it's true that a new Assassin's Creed is coming this year. Then... well, you can't really compare AC and MK, they're way too different.
Edit: Forgot Batman Arkham City, this one will be nice as well. Still not as nice as MK9, of course.