Heroes mode is really all I play because you can get by and deal with all the bugs and such cause of your higher health. Also once you really get Heroes mode downpacked it's really fun. Leon is also my favorite RE character so I go crazy when I play as him.
Loudout recommended for Heroes:
Juggernaut
Samurai Edge
Leon (Spec Ops) with Super Soldier
Nicholai or HUNK (USS). Give Nicholai Attraction Pheromone and give HUNK Active Camo.
As a normal USS or Spec Ops:
Lupo or Dee-Ay with Super Soldier
Hammer
Samurai Edge
Super Soldier is by far the best ability in my opinion. I demonstrate its awesomeness in my video.
http://www.youtube.com/watch?v=XZg5-nm-65Q
If you're a hero only use Super Soldier against other heroes. Melee regular opponents and finish them off quickly with the execution that you have to hold B for. And if you are a regular dude NEVER melee a hero. It NEVER works out.