No one. No one needs to die forever. Will some? Sure. But do they need to? No. Every character has fans, whether you believe it or not. Just because you don't like them doesn't mean no one does. Yeah, some of the characters of this franchise aren't that popular, and they aren't relevant to the story, and they just suck. But this is a new storyline, and characters have already been improved (Stryker for instance), so that means many more characters from the post-UMK3 era can be turned into good characters. They all deserve a chance, not permanent death. If they do get remade and still suck, then they can die.
Except for Hsu Hao. He's already dead.