This is my dreamcanon/fanfiction for MK11:
4. Liu Kang
5. Shang Tsung
17. Cassie Cage
19. Kung Jin
21. Kotal Kahn
22. Erron Black
25. New Edenian character (Mysterious Woman from Jade's MK9 ending?)
26. New Netherrealm character (maybe an Oni done right)
27. New Orderrealm character (a young Seido guardsman with doubts about Hotaru's methods)
28. New Edenian or Netherrealm character
MK11 will definitely have more characters than MKX at launch if it stays current-gen, so 28 total instead of the usual 24. Less new characters than MKX because lots of new characters was MKX's thing. NRS will build on the new generation, but there's a large foundation as is.
My wishes for the plot of MK11 is something relating to Edenia, so with that in mind... my idea is that Liu Kang and Kitana try to expand their newfound empire by merging it with other realms. Liu targets Earthrealm, believing they will be better off under his rule, while Kitana goes for her homeland. Kitana succeeds in separating Edenia from Outworld and tries to merge it with the Netherrealm. Tanya and Rain will fight her, while Ermac (Jerrod) and Sindel are stuck between helping their daughter and saving Edenia. One or two of the new characters are Edenian, including the mysterious woman from Jade's MK9 ending.
D'Vorah, being a Shinnok groupie, would assist Shinnok's replacements, and so will side with Kitana and Liu Kang. D'Vorah and Tanya rivalry can be a thing.
Because Outworld loses Edenia, Kotal Kahn gets into the fray with his goons Erron and Ferra & Torr (now with bigger roles, hopefully).
Johnny, Sonya, Jax and Kenshi have retired, but Cassie's team, along with Raiden and Fujin, fights off Liu Kang's advances on Earth. They might initially intervene in Edenia until Earth is threatened. Raiden becomes more and more desperate, to the point of causing more harm than good, and in the end is succeeded by Fujin.
Shang Tsung comes back somehow and participates in the conflict, possibly coming over to the forces of good to battle Liu, like in his MK9 ladder ending. Cyrax joins Cassie's team, as he joined the SF in the old timeline. These guys are basically here because they are hugely popular and missing two straight games would be a disservice, plus a game needs at least one sorcerer and one robot.
Hotaru and his lieutenant aid Kotal to preserve order among the realms, and because Kotal is all about keeping things on the straight and narrow. At some point, Hotaru becomes a liability.
Havik stirs the whole thing up. He suggests the idea of conquering to Liu and Kitana. He participates on every side, causing as much chaos as possible.
D'Vorah, Smoke, Sindel, Kitana and a new Netherrealm character(s) help Liu Kang.
Frost and Smoke (once he loses revenant status) flesh out Sub-Zero's storyline.
Sub-Zero, Scorpion, Ermac, Smoke, Rain, Cyrax = plenty of ninjas for the casuals.